Plot
Gru meets his long-lost, charming, cheerful, and more successful twin brother Dru, who wants to team up with him for one last criminal heist.
Cast
| Name | Role |
|---|---|
| Steve Carell | Gru / Dru |
| Kristen Wiig | Lucy |
| Trey Parker | Balthazar Bratt |
| Miranda Cosgrove | Margo |
| Dana Gaier | Edith |
| Nev Scharrel | Agnes |
| Pierre Coffin | Minions / Museum Director / Additional Voices |
| Steve Coogan | Fritz / Silas Ramsbottom |
| Julie Andrews | Gru's Mom |
| Jenny Slate | Valerie Da Vinci |
| Michael Beattie | TV Show Host / Scar-Faced Man |
| Andy Nyman | Clive the Robot |
| Adrian Ciscato | Niko |
| Brian T. Delaney | Commercial Announcer / Military Officer / Additional Voices |
| Katia Saponenko | Niko's Mother |
| Ken Daurio | Celebrity |
| Jude Alpers | Commercial Kid |
| Cory Walls | Vincenzo |
| Sophie M. Siadatpour | Little Girl |
| Lori Alan | Additional Voices |
| Carlos Alazraqui | Additional Voices |
| Kyle Balda | Additional Voices |
| Bob Bergen | Additional Voices |
| Gregg Berger | Additional Voices |
| John Cygan | Additional Voices |
| Bill Farmer | Additional Voices |
| Danny Mann | Additional Voices |
| Stephanie De Meautis | Additional Voices |
| Bruno Dequier | Additional Voices |
| Teresa Ganzel | Additional Voices |
| Jess Harnell | Additional Voices |
| John Kassir | Additional Voices |
| Mona Marshall | Additional Voices |
| Laraine Newman | Additional Voices |
| Jan Rabson | Additional Voices |
| Mindy Sterling | Additional Voices |
| Tara Strong | Additional Voices |
| Jim Ward | Additional Voices |
| Rene Bitorajac | Gru |