Plot
A strange black entity from another world bonds with Peter Parker and causes inner turmoil as he contends with new villains, temptations, and revenge.
Cast
| Name | Role |
|---|---|
| Tobey Maguire | Spider-Man / Peter Parker |
| Kirsten Dunst | Mary Jane Watson |
| James Franco | New Goblin / Harry Osborn |
| Thomas Haden Church | Sandman / Flint Marko |
| Topher Grace | Venom / Eddie Brock |
| Bryce Dallas Howard | Gwen Stacy |
| Rosemary Harris | May Parker |
| J.K. Simmons | J. Jonah Jameson |
| James Cromwell | Captain Stacy |
| Theresa Russell | Emma Marko |
| Dylan Baker | Dr. Curt Connors |
| Bill Nunn | Joseph 'Robbie' Robertson |
| Bruce Campbell | Maître d' |
| Elizabeth Banks | Miss Brant |
| Ted Raimi | Hoffman |
| Perla Haney-Jardine | Penny Marko |
| Willem Dafoe | Green Goblin / Norman Osborn |
| Cliff Robertson | Ben Parker |
| Elya Baskin | Mr. Ditkovitch |
| Mageina Tovah | Ursula |
| John Paxton | Houseman |
| Becky Ann Baker | Mrs. Stacy |
| Stan Lee | Man in Times Square |
| Michael Papajohn | Dennis Carradine / Carjacker |
| Joe Manganiello | Flash Thompson |
| Hal Fishman | Anchorman |
| Lucy Gordon | Jennifer Dugan |
| Steve Valentine | Photographer |
| Tim Maculan | Play Director |
| Marc Vann | Play Producer |
| Joe Bays | Jazz Club Manager |
| Gregg Daniel | Precinct Detective |
| Rogelio T. Ramos | Emergency Room Doctor |
| Timothy Patrick Quill | Crane Operator |
| Menachem Mendel Boymelgreen | Kid in Times Square |
| Nasir Stewart | Kid in Times Square |
| Austin Hendrickson | Kid in Times Square |
| Taylor Hemhauser | Kid in Times Square |
| Kathryn Bryding | Woman Outside Theater |
| Joe Virzi | Police Detective |
| Bill E. Rogers | New Jersey State Policeman |
| Michael Alexander | New Jersey State Policeman |
| April Parker Jones | Test Site Technician |
| Edward Padilla | Test Site Technician |
| Robert Curtis Brown | Test Site Technician |
| Paul Terrell Clayton | Test Site Technician |
| Carolyn Neff | Test Site Technician |
| Christina Cindrich | Test Site Technician |
| Sonya Maddox | ICU Nurse |
| Andre B. Blake | Crane Disaster Radio Policeman |
| Derrick 'Phoenix' Thomas | Cop at Crane Disaster |
| Jessi Collins | Mary Jane's Replacement |
| Michael McLaughlin | Boy at Keys to the City Ceremony |
| Anne Gartlan | Councilwoman |
| Emilio Rivera | Policeman at Sand Truck |
| Keith Woulard | Policeman at Sand Truck |
| Reynaldo Gallegos | Armored Car Driver |
| Jim Coope | Newsstand Patron |
| Dean Edwards | Newsstand Patron |
| Margaret Laney | Newsstand Patron |
| Toni Wynne | Congratulatory Woman at Daily Bugle |
| Aimee Miles | Coffee Shop Waitress |
| Tanya Bond | Jazz Club Waitress |
| Mark Kubr | Jazz Club Bouncer |
| Emma Raimi | Girl with Camera |
| Lorne Raimi | Boy at the Final Battle |
| Henry Raimi | Boy at the Final Battle |
| Samantha Ressler | Girl at the Final Battle |
| Alan Cohn | Jazz Club Musician |
| Dan Callahan | Jazz Club Musician |
| Ron King | Jazz Club Musician |
| Carol Chaikin | Jazz Club Musician |
| Dan Cummings | Jazz Club Musician |
| Vance Hammond | Jazz Club Musician |
| Ramon Adams | Businessman |
| A.J. Adelman | Theater Attendee |
| Angelis Alexandris | Pedestrian |
| Dawn Marie Anderson | I.C.U Nurse |
| Frank Anello | NYPD Officer |
| Anya Avaeva | Model |
| David Backus | Bucket Boy |
| Tiffany L. Baker | News Reporter |
| Tony Besson | Photoshoot Client |
| Gerald Bunsen | British Publish Officer |
| Marc C. Cancassi | Photographer |
| Sujeilee Candele | Rescued Girl |
| Kadrolsha Ona Carole | Photographer |
| Michael Ciesla | Photographer |
| Kristi Clainos | Faye Miller |
| David Collihan | Theatre-Goer |
| Marmee Regine Cosico | Park Goer |
| Tom Coughlin | Parade Watcher |
| John Crann | Theatre Patron |
| Crystal Marie Denha | Jazz Club Girl |
| Ev Depaolis | Beautiful Woman |
| Amy V. Dewhurst | Columbia Grad Student |
| Cesar Di Parra | Bartender |
| Ryan Dillon | Chester - Parade Watcher |
| Emily Eckes | Beautiful Woman |
| Paul Edney | New York City Commuter / Driver |
| Natalie Fabry | Girl at Key Ceremony |
| Keith Fausnaught | Pedestrian |
| Gary Flamik | Pedestrian. |
| Amanda Florian | A Spidey Kid |
| Brianna Leann Florian | A Spidey Kid |
| Tiffany Ashley Florian | A Spidey Kid |
| Shaun Patrick Flynn | Business Man |
| Logan Fry | Automobile Driver |
| Kevin Fung | Spectator |
| Tony Galtieri | News Spectator |
| Chuck Gerena | Funeral Limo Driver |
| Halla | Jazz Club Guest |
| Brian Hopson | News Reporter |
| Claude Jay | Cop at the rescue of May Jane Watson |
| Julie Jei | Female New Yorker |
| Irina Costa Jelinek | Jazz Club Waitress |
| Jhing | Jazz Club Singing Waitress |
| Andrew James Jones | Jazz Club Bouncer |
| Natali Jones | Girl at Key Ceremony |
| Christopher Jude | Student |
| Samantha Kelly | Parade Watcher |
| Brittany Krall | ER Nurse |
| Alyssa Lakota | Dog Walker |
| Tia Latrell | Observer |
| Linda Lee | Businesswoman |
| Pierangeli Llinas | Woman in Court |
| Bernadette Lords | British Publicist |
| Sandrine Marlier | Shocked pedestrian |
| Laura McDavid | Journalist |
| Natalie McNeil | Girl Screaming in Camaro |
| Daniel Mignault | Kid in Times Square |
| Martha Millan | Oscorp Receptionist |
| Michele-Nanette Miller | Girl in Times Square |
| Claudia Katz Minnick | Robbie's Assistant |
| Robert Myers | Theatergoer |
| Joseph O'Brien | Businessman |
| Jen Oda | Beautiful Girl |
| Anjelia Pelay | Beautiful Woman |
| Roger Petan | Pedestrian |
| Nick Poltoranin | Police Officer |
| Don Pravda | News Reporter Photographer |
| Ryan Ramirez | Blonde Parade Watcher |
| Vanessa Reseland | Beautiful Woman |
| La Rivers | Beautiful Woman |
| Bria Roberts | Business Woman |
| Luis Rosa | Pedestrian |
| Austin Rospert | Pedestrian |
| Vanessa Ross | Sandman Victim |
| Brenna Roth | Bad Girl |
| Shade Rupe | City Hall Cheerer |
| Arick Salmea | Guy with Ticket |
| Eric Shackelford | Jazz Club Beatnik |
| Daniel Shafer | Jazz Club Guest |
| Abbey Skinner | Café Girl |
| Kristin Somo | Jazz Club Patron |
| Jennifer Sparks | Jazz Club Waitress |
| Christopher Stadulis | Firefighter |
| Jimmy Star | Police Officer |
| Arne Starr | Broadway's Audience Member |
| Liam Stone | Jazz Club Musician |
| Tajna Tanovic | Girl in Cab |
| Aija Terauda | Model |
| Brigid Turner | Hot Girl |
| Philip Vaiman | Violinist |
| Jeshua Vargas | Party Goer |
| Veronica | Dog |
| Nick Vlassopoulos | Barpatron #5 |
| Sincerely A. Ward | Model |
| Silq Webster | Model |
| Graig F. Weich | Student |
| Fredrick Weiss | Restaurant Patron |
| Jennifer Weston | Emergency Room Nurse |
| Trenton Willey | City Hall Cheerer |
| Ray Wineteer | Spectator |